Shaping Durum Wheat for the Future: Gene Expression Analyses and Metabolites Profiling Support the Contribution of BCAT Genes to Drought Stress Response
global climate change, its implications for agriculture, and complex scenarios presented by the scientific community to the attention of the whole world. Drought is a major abiotic stress which can limit growth and yield, so the identification of genotypes with a higher adaptation to drought is one of the major objectives in breeding programs. During abiotic stress, metabolic adaptation is very important for stress tolerance, and specific accumulation of amino acids and / or as secondary metabolites derived from the metabolism of amino acids can be correlated with increased tolerance to adverse environmental conditions.
This work, focused on the metabolism of branched chain amino acids (BCAA) in durum wheat and the role of branched-chain amino acid aminotransferase (BCATs) in response to stress. BCATs role in response to drought crops previously proposed for Arabidopsis, in which the BCAA levels are altered in the level of transcription in drought conditions, lead to metabolic defense response. However, the role of BCAA wheat as drought triggers defense responses have not been described. Comparative genomic approaches described composition BCAT gene family in durum wheat.
Here we show the tissue and developmental stage specificity BCATs regulation in response to drought. In addition, metabolite profiling was performed on two contrasting cultivars of durum wheat Cappelli Colosseo and resulted in detection of a specific pattern of metabolites accumulated between genotype and, in particular, in enhanced BCAA accumulated in Cappelli tolerant cv further supports the role of BCAAs in defense responses to drought. The results support the use of gene expression and metabolomics in modern breeding objectives to form new cultivars that are more resistant to climate change.

Gene expression profiles of cardiomyocytes hypertrophic identify new players in the pathological remodeling
Objective: pathological cardiac remodeling characterized by cardiomyocyte hypertrophy and activation of fibroblasts, which in turn can lead to maladaptive hypertrophy and heart failure (HF). Genome-wide expression analysis in cardiac tissue has been instrumental to the identification of molecular mechanisms play. However, the data is based on signals originating from all types of heart cells. Here we are aiming for a more detailed view of the molecular changes driving maladaptive cardiomyocyte hypertrophy to aid in the development of therapies to reverse the pathological remodeling.
Methods and results: Utilizing special cardiomyocyte reporter mice exposed to pressure overload by aortic cross-appeal and cardiomyocyte isolation by flow cytometry, we obtained gene expression profiles of hypertrophic cardiomyocytes in a faster pace after the stress and pathological hypertrophy of cardiomyocytes show. We identified a subset of genes differentially regulated and specific to either stage.
Among the specific genes upregulated in cardiomyocytes during maladaptive phase we found a stress marker is known, as Nppb and Myh7, but also identified a set of genes with unknown role in pathological hypertrophy, including platelet isoform of phosphofructokinase (PFKP). norepinephrine-angiotensin II treatment of cultured human cardiomyocytes due to the secretion of NT pro-BNP and recapitulation upregulation of this gene, suggesting conservation failed upregulation in cardiomyocytes. In addition, several genes induced during pathological hypertrophy was also found elevated in human heart failure, with their expression was positively correlated with stress markers known NPPB and MYH7.
![]() ABIN3 Antibody |
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5303-002mg | ProSci | 0.02 mg | EUR 171.82 |
Description: ABIN3 Antibody: The nuclear factor NF-κB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-κB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-κB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-κB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-κB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-κB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist. |
![]() ABIN3 Antibody |
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5303-01mg | ProSci | 0.1 mg | EUR 436.42 |
Description: ABIN3 Antibody: The nuclear factor NF-κB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-κB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-κB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-κB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-κB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-κB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist. |
![]() ABIN3 Peptide |
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5303P | ProSci | 0.05 mg | EUR 164.75 |
Description: (CT) ABIN3 peptide |
![]() VEGF Rabbit Polyclonal Antibody |
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ES8453-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against VEGF Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() VEGF Rabbit Polyclonal Antibody |
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ES8453-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against VEGF Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() CD10 Rabbit Polyclonal Antibody |
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ES8454-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against CD10 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() CD10 Rabbit Polyclonal Antibody |
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ES8454-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against CD10 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NM23A Rabbit Polyclonal Antibody |
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ES8455-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against NM23A Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NM23A Rabbit Polyclonal Antibody |
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ES8455-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against NM23A Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATM Rabbit Polyclonal Antibody |
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ES8456-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATM Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATM Rabbit Polyclonal Antibody |
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ES8456-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATM Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATM Rabbit Polyclonal Antibody |
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ES8457-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATM Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATM Rabbit Polyclonal Antibody |
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ES8457-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATM Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() HSC70 Rabbit Polyclonal Antibody |
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ES8558-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against HSC70 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() HSC70 Rabbit Polyclonal Antibody |
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ES8558-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against HSC70 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() HSP40 Rabbit Polyclonal Antibody |
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ES8559-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against HSP40 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() HSP40 Rabbit Polyclonal Antibody |
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ES8559-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against HSP40 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() HSP90? Rabbit Polyclonal Antibody |
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ES8560-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against HSP90? Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() HSP90? Rabbit Polyclonal Antibody |
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ES8560-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against HSP90? Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() IkB ? Rabbit Polyclonal Antibody |
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ES8561-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against IkB ? Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() IkB ? Rabbit Polyclonal Antibody |
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ES8561-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against IkB ? Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() JAK1 Rabbit Polyclonal Antibody |
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ES8562-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against JAK1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() JAK1 Rabbit Polyclonal Antibody |
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ES8562-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against JAK1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() JAK2 Rabbit Polyclonal Antibody |
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ES8563-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against JAK2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() JAK2 Rabbit Polyclonal Antibody |
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ES8563-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against JAK2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() JNK2 Rabbit Polyclonal Antibody |
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ES8564-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against JNK2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() JNK2 Rabbit Polyclonal Antibody |
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ES8564-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against JNK2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() JNK3 Rabbit Polyclonal Antibody |
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ES8565-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against JNK3 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() JNK3 Rabbit Polyclonal Antibody |
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ES8565-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against JNK3 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() MEK2 Rabbit Polyclonal Antibody |
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ES8566-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against MEK2 Rabbit from Human. This antibody is tested and validated for WB, ELISA, IHC |
![]() MEK2 Rabbit Polyclonal Antibody |
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ES8566-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against MEK2 Rabbit from Human. This antibody is tested and validated for WB, ELISA, IHC |
![]() MEK3 Rabbit Polyclonal Antibody |
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ES8567-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against MEK3 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() MEK3 Rabbit Polyclonal Antibody |
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ES8567-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against MEK3 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Nrf2 Rabbit Polyclonal Antibody |
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ES8568-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Nrf2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Nrf2 Rabbit Polyclonal Antibody |
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ES8568-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Nrf2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4a Rabbit Polyclonal Antibody |
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ES8569-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG4a Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4a Rabbit Polyclonal Antibody |
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ES8569-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG4a Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4b Rabbit Polyclonal Antibody |
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ES8570-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG4b Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4b Rabbit Polyclonal Antibody |
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ES8570-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG4b Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4c Rabbit Polyclonal Antibody |
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ES8571-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG4c Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG4c Rabbit Polyclonal Antibody |
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ES8571-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG4c Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG5 Rabbit Polyclonal Antibody |
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ES8572-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG5 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG5 Rabbit Polyclonal Antibody |
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ES8572-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG5 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG7 Rabbit Polyclonal Antibody |
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ES8573-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG7 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG7 Rabbit Polyclonal Antibody |
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ES8573-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG7 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG13 Rabbit Polyclonal Antibody |
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ES8574-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG13 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG13 Rabbit Polyclonal Antibody |
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ES8574-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG13 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG13 Rabbit Polyclonal Antibody |
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ES8575-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG13 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG13 Rabbit Polyclonal Antibody |
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ES8575-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG13 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG14L Rabbit Polyclonal Antibody |
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ES8576-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ATG14L Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ATG14L Rabbit Polyclonal Antibody |
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ES8576-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ATG14L Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NBR1 Rabbit Polyclonal Antibody |
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ES8578-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against NBR1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NBR1 Rabbit Polyclonal Antibody |
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ES8578-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against NBR1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NBR1 Rabbit Polyclonal Antibody |
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ES8579-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against NBR1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() NBR1 Rabbit Polyclonal Antibody |
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ES8579-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against NBR1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() WIPI2 Rabbit Polyclonal Antibody |
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ES8580-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against WIPI2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() WIPI2 Rabbit Polyclonal Antibody |
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ES8580-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against WIPI2 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Gab1 Rabbit Polyclonal Antibody |
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ES8582-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Gab1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Gab1 Rabbit Polyclonal Antibody |
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ES8582-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Gab1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ERK1 Rabbit Polyclonal Antibody |
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ES8583-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against ERK1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() ERK1 Rabbit Polyclonal Antibody |
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ES8583-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against ERK1 Rabbit from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() IBA1 Polyclonal Rabbit Antibody |
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RA22133 | Neuromics | 100 ul | EUR 435 |
![]() GAPDH Rabbit Polyclonal Antibody |
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A01021-005ml | Abbkine | 0.05ml | EUR 147 |
Description: A polyclonal antibody for detection of GAPDH from Human, Mouse, Rat, Rabbit, Chicken, Monkey, Sheep, Xneous. This GAPDH antibody is for WB, IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() GAPDH Rabbit Polyclonal Antibody |
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A01021-02ml | Abbkine | 0.2ml | EUR 332 |
Description: A polyclonal antibody for detection of GAPDH from Human, Mouse, Rat, Rabbit, Chicken, Monkey, Sheep, Xneous. This GAPDH antibody is for WB, IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() GAPDH Rabbit Polyclonal Antibody |
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A01021-02ml5 | Abbkine | 0.2ml×5 | EUR 920 |
Description: A polyclonal antibody for detection of GAPDH from Human, Mouse, Rat, Rabbit, Chicken, Monkey, Sheep, Xneous. This GAPDH antibody is for WB, IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() Met Rabbit Polyclonal Antibody |
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ABP57458-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of Met from Human, Mouse, Rat. This Met antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Met of MET |
![]() Met Rabbit Polyclonal Antibody |
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ABP57458-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of Met from Human, Mouse, Rat. This Met antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Met of MET |
![]() Met Rabbit Polyclonal Antibody |
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ABP57458-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of Met from Human, Mouse, Rat. This Met antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Met of MET |
![]() VEGF Rabbit Polyclonal Antibody |
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ABP57460-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of VEGF from Human, Mouse, Rat. This VEGF antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of VEGF of VEGFA |
![]() VEGF Rabbit Polyclonal Antibody |
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ABP57460-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of VEGF from Human, Mouse, Rat. This VEGF antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of VEGF of VEGFA |
![]() VEGF Rabbit Polyclonal Antibody |
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ABP57460-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of VEGF from Human, Mouse, Rat. This VEGF antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of VEGF of VEGFA |
![]() CD10 Rabbit Polyclonal Antibody |
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ABP57461-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of CD10 from Human, Mouse, Rat. This CD10 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of CD10 of MME |
![]() CD10 Rabbit Polyclonal Antibody |
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ABP57461-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of CD10 from Human, Mouse, Rat. This CD10 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of CD10 of MME |
![]() CD10 Rabbit Polyclonal Antibody |
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ABP57461-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of CD10 from Human, Mouse, Rat. This CD10 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of CD10 of MME |
![]() NM23A Rabbit Polyclonal Antibody |
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ABP57462-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of NM23A from Human, Mouse, Rat. This NM23A antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of NM23A of NME1 |
![]() NM23A Rabbit Polyclonal Antibody |
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ABP57462-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of NM23A from Human, Mouse, Rat. This NM23A antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of NM23A of NME1 |
![]() NM23A Rabbit Polyclonal Antibody |
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ABP57462-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of NM23A from Human, Mouse, Rat. This NM23A antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of NM23A of NME1 |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57463-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57463-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57463-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57464-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57464-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() ATM Rabbit Polyclonal Antibody |
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ABP57464-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of ATM from Human, Mouse, Rat. This ATM antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of ATM of ATM |
![]() HSC70 Rabbit Polyclonal Antibody |
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ABP57565-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of HSC70 from Human, Mouse, Rat. This HSC70 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) |
![]() HSC70 Rabbit Polyclonal Antibody |
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ABP57565-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of HSC70 from Human, Mouse, Rat. This HSC70 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) |
![]() HSC70 Rabbit Polyclonal Antibody |
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ABP57565-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of HSC70 from Human, Mouse, Rat. This HSC70 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) |
![]() HSP40 Rabbit Polyclonal Antibody |
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ABP57566-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of HSP40 from Human, Mouse, Rat. This HSP40 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP40 |
![]() HSP40 Rabbit Polyclonal Antibody |
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ABP57566-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of HSP40 from Human, Mouse, Rat. This HSP40 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP40 |
![]() HSP40 Rabbit Polyclonal Antibody |
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ABP57566-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of HSP40 from Human, Mouse, Rat. This HSP40 antibody is for WB, IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP40 |
![]() HSP90Alpha Rabbit Polyclonal Antibody |
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ABP57567-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of HSP90Alpha from Human, Mouse, Rat. This HSP90Alpha antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP90? |
![]() HSP90Alpha Rabbit Polyclonal Antibody |
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ABP57567-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of HSP90Alpha from Human, Mouse, Rat. This HSP90Alpha antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP90? |
![]() HSP90Alpha Rabbit Polyclonal Antibody |
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ABP57567-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of HSP90Alpha from Human, Mouse, Rat. This HSP90Alpha antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of HSP90? |
![]() JAK1 Rabbit Polyclonal Antibody |
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ABP57569-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK1 |
![]() JAK1 Rabbit Polyclonal Antibody |
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ABP57569-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK1 |
![]() JAK1 Rabbit Polyclonal Antibody |
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ABP57569-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of JAK1 from Human, Mouse, Rat. This JAK1 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK1 |
![]() JAK2 Rabbit Polyclonal Antibody |
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ABP57570-003ml | Abbkine | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of JAK2 from Human, Mouse, Rat. This JAK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK2 |
![]() JAK2 Rabbit Polyclonal Antibody |
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ABP57570-01ml | Abbkine | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of JAK2 from Human, Mouse, Rat. This JAK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK2 |
![]() JAK2 Rabbit Polyclonal Antibody |
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ABP57570-02ml | Abbkine | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of JAK2 from Human, Mouse, Rat. This JAK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein of JAK2 |
Mechanically, the suppression Pfkp in primary cardiomyocytes attenuated stress gene expression and hypertrophy, suggesting that Pfkp an important new player in the renovation of pathological cardiomyocyte.