Description: Human Fibroblast growth factor receptor 1 (FGFR1), also known as BFGFR, CD331, CEK and FLT2, GenBank Accession No. NM_0023110.3, a.a. 399-822(end), with C-terminal Avi-His-tag, co-expressed with PTP1B for dephosphorylation in an Sf9 cell expression system. Percentage of phosphorylation ≤5% and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW=51 kDa.

Description: Human Fibroblast growth factor receptor 1 (FGFR1), also known as BFGFR, CD331, CEK and FLT2, GenBank Accession No. NM_0023110.3, a.a. 399-822(end), with C-terminal Avi-His-tag, co-expressed with PTP1B for dephosphorylation in an Sf9 cell expression system. Percentage of phosphorylation ≤5% and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW=51 kDa.

Description: Recombinant IL-1 beta is a disulfide-linked monomer protein consisting of two 153 amino acid residues. Recombinant IL-1 beta migrates as an approximately 17 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding murine Interleukin-1 beta mature chain was expressed in E. coli. _x000D__x000D_

Description: Recombinant IL-1 beta is a disulfide-linked monomer protein consisting of two 153 amino acid residues. Recombinant IL-1 beta migrates as an approximately 17 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding murine Interleukin-1 beta mature chain was expressed in E. coli. _x000D__x000D_

Description: Recombinant murine stromal cell-derived factor-1beta (SDF1β), also known as CXCL12 or Pre-B cell growth-stimulating factor (PBSF), is a disulfide-linked monomeric protein consisting of 73 a.a. and migrates as an approximately 8 kDa protein under reducing and non-reducing conditions. Optimized DNA sequence encoding mouse Stromal Cell-Derived Factor-1 beta (SDF1β) mature chain was expressed in E. coli.

Description: Recombinant murine stromal cell-derived factor-1beta (SDF1β), also known as CXCL12 or Pre-B cell growth-stimulating factor (PBSF), is a disulfide-linked monomeric protein consisting of 73 a.a. and migrates as an approximately 8 kDa protein under reducing and non-reducing conditions. Optimized DNA sequence encoding mouse Stromal Cell-Derived Factor-1 beta (SDF1β) mature chain was expressed in E. coli.

Description: Dephosphorylated recombinant FGFR3 (Fibroblast Growth Factor Receptor 3) encompassing amino acids 397-806. This protein contains an N-terminal His-Tag and has been biotinylated using an N-terminal Avi-Tag™. The recombinant protein is purified to ≥90%

Description: Mouse 14-3-3 alpha/beta Protein, GenBank Accession No. NM_018753, full length, with N-terminal His tag, expressed in Sf9 insect cells using baculovirus. MW = 32 kDa.

Description: Human Fibroblast growth factor receptor 3 (FGFR3), also known as JTK4, CD333, CEK2 and ACH, GenBank Accession No. NM_00142, a.a. 447-761, with N-terminal His-Avi-tag, expressed in an Sf9 infected baculovirus expression system and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW = 39 kDa. This protein was isolated from a co-expression with PTP1B. Percentage of phosphorylation ≤5%.

Description: Description of target: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.061 ng/mL

Description: Dephosphorylated recombinant FGFR3 (Fibroblast Growth Factor Receptor 3) encompassing amino acids 397-806. This protein contains the pathogenic mutation N540K in the tyrosine kinase domain. It also contains an N-terminal His-Tag. This protein was co-expressed with PTP1B for dephosphorylation. Phosphorylation level confirmed to be <5%. The protein is biotinylated using an N-terminal Avi-Tag™.