Predicting brain metastasis in early stage non-small cell lung cancer patients by gene expression profiling

Background: Non-small cell lung cancer (NSCLC) is the most common cause of cancer-deaths due to early metastatic spread, in many cases, especially to the brain. The pattern of the spread of disease-specific organ may be driven by the activity of specific signaling pathway in the primary tumor. We aim to identify gene expression signatures and the relevant signal associated with the development of brain metastasis (BM) after surgical resection of NSCLC.


Methods: frozen Fast NSCLC surgical specimens obtained from the tumor bank. RNA was extracted and analyzed by RNA-sequencing (Illumina HiSeq 2500). clinical parameters and gene expression examined to distinguish between patients with BM, patients with metastasis to sites other than the brain, and patients who do not develop metastatic disease in a significant clinical follow-up. Study component analysis and principal enrichment lines do.


Results: A total of 91 patients were included in this study, 32 of which were developed BM. The stage of disease at diagnosis (P = 0.004) and the degree of differentiation (P = 0.007) were significantly different between BM and control groups. We identified a set of 22 genes that are associated specifically with the BM, and not with metastasis to other sites. This sets reached 93.4% accuracy (95% CI: 86.2 to 97.5%), 96.6% specificity and 87.5% sensitivity of identifying the correct patient BM in the analysis of the internal validation leave-one-out , The oxidative phosphorylation pathway was highly correlated with the risk of BM.


Conclusion:
The expression level of a small set of genes from the primary tumor was found to predict the development of BM, clear of metastasis to other organs. Oxidative phosphorylation correlated genes and pathways require further validation as a useful predictor of the clinical potential of BM and perhaps as a new therapeutic target for the prevention of BM.

Predicting brain metastasis in early stage non-small cell lung cancer patients by gene expression profiling
Predicting brain metastasis in early stage non-small cell lung cancer patients by gene expression profiling

Gene expression profile identifies Zac1 role in metastatic cervical cancer

Zinc-finger proteins that regulate apoptosis and cell cycle arrest 1 (Zac1), encoded by the gene Plagl1, is a transcription factor of seven zinc-finger-containing belong printed genome and is expressed in various types of human embryonic and adult tissue. Zac1 is postulated be a tumor suppressor by inducing cell cycle arrest and apoptosis through interacting and modulating the transcriptional activity of p53 as named.

Correspondingly, reduction or loss of expression Zac1 associated with the occurrence and development of some human tumors, including cervical cancer, breast cancer, ovarian cancer, pituitary tumors and basal cell carcinoma, implying rationality of utilizing the expression Zac1 as a biomarker novel for evaluating the prognosis of cervical cancer.

However, until now, has not been clarified whether Zac1 expression associated with the prognosis of patients in clinical cervical cancer tumor samples. To answer the questions outlined above, we report here a comprehensive investigation Zac1 expression in biopsies of cervical carcinoma clinical. By analyzing the expression Zac1 in a variety of gene expression profiling of cervical cancer database, we demonstrated an association between high Zac1 expression and poor prognosis of cervical cancer.

RUSC1 Antibody (Rabbit Polyclonal)

MBS8507686-01mLAF635 0.1mL(AF635)
EUR 565

RUSC1 Antibody (Rabbit Polyclonal)

MBS8507686-02mL 0.2mL
EUR 345

RUSC1 Polyclonal Antibody

A60750
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

RUSC1 Polyclonal Antibody

28956 100ul
EUR 439

RUSC1 Polyclonal Antibody

28956-100ul 100ul
EUR 302.4

RUSC1 Polyclonal Antibody

28956-50ul 50ul
EUR 224.4

RUSC1 Polyclonal Antibody

E915417 100ul
EUR 225
Description: Available in various conjugation types.

RUSC1 Polyclonal Antibody

E-AB-19038-120uL 120uL
EUR 240
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-19038-200uL 200uL
EUR 399
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-19038-20uL 20uL
EUR 73
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-19038-60uL 60uL
EUR 143
Description: Unconjugated

RUSC1 Polyclonal Antibody

A72196 50 μl
EUR 408

RUSC1 Polyclonal Antibody

E-AB-65309-120uL 120uL
EUR 320
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-65309-200uL 200uL
EUR 530
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-65309-60uL 60uL
EUR 200
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-65309-each each Ask for price
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-52951-120uL 120uL
EUR 240
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-52951-200uL 200uL
EUR 399
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-52951-20uL 20uL
EUR 73
Description: Unconjugated

RUSC1 Polyclonal Antibody

E-AB-52951-60uL 60uL
EUR 143
Description: Unconjugated

RUSC1 Polyclonal Antibody

MBS9234811-01mL 0.1mL
EUR 415

RUSC1 Polyclonal Antibody

MBS9234811-5x01mL 5x0.1mL
EUR 1841

RUSC1 Polyclonal Antibody

MBS9135403-002mL 0.02mL
EUR 200

RUSC1 Polyclonal Antibody

MBS9135403-005mL 0.05mL
EUR 255

RUSC1 Polyclonal Antibody

MBS9135403-01mL 0.1mL
EUR 345

RUSC1 Polyclonal Antibody

MBS9135403-02mL 0.2mL
EUR 545

RUSC1 Polyclonal Antibody

MBS9135403-5x02mL 5x0.2mL
EUR 2265

RUSC1 Polyclonal Antibody

MBS8570099-01mL 0.1mL
EUR 305

RUSC1 Polyclonal Antibody

MBS8570099-01mLAF405L 0.1mL(AF405L)
EUR 565

RUSC1 Polyclonal Antibody

MBS8570099-01mLAF405S 0.1mL(AF405S)
EUR 565

RUSC1 Polyclonal Antibody

MBS8570099-01mLAF610 0.1mL(AF610)
EUR 565

RUSC1 Polyclonal Antibody

MBS8570099-01mLAF635 0.1mL(AF635)
EUR 565

RUSC1 Polyclonal Antibody

MBS2562853-002mL 0.02mL
EUR 135

RUSC1 Polyclonal Antibody

MBS2562853-006mL 0.06mL
EUR 190

RUSC1 Polyclonal Antibody

MBS2562853-012mL 0.12mL
EUR 265

RUSC1 Polyclonal Antibody

MBS2562853-02mL 0.2mL
EUR 415

RUSC1 Polyclonal Antibody

MBS2562853-5x02mL 5x0.2mL
EUR 1835

RUSC1 Polyclonal Antibody

MBS2560927-002mL 0.02mL
EUR 135

RUSC1 Polyclonal Antibody

MBS2560927-006mL 0.06mL
EUR 190

RUSC1 Polyclonal Antibody

MBS2560927-012mL 0.12mL
EUR 265

RUSC1 Polyclonal Antibody

MBS2560927-02mL 0.2mL
EUR 415

RUSC1 Polyclonal Antibody

MBS2560927-5x02mL 5x0.2mL
EUR 1835

RUSC1 Polyclonal Antibody

MBS2555683-006mL 0.06mL
EUR 190

RUSC1 Polyclonal Antibody

MBS2555683-012mL 0.12mL
EUR 265

RUSC1 Polyclonal Antibody

MBS2555683-02mL 0.2mL
EUR 415

RUSC1 Polyclonal Antibody

MBS2555683-5x02mL 5x0.2mL
EUR 1835

RUSC1 Polyclonal Antibody

MBS9432550-005mL 0.05mL
EUR 300

RUSC1 Polyclonal Antibody

MBS9432550-01mL 0.1mL
EUR 390

RUSC1 Polyclonal Antibody

MBS9432550-5x01mL 5x0.1mL
EUR 1610

RUSC1 Polyclonal Antibody

RD219038A-120uL 120μL
EUR 360
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD219038A-200uL 200μL
EUR 630
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD219038A-20uL 20μL
EUR 109.5
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD219038A-60uL 60μL
EUR 214.5
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD252951A-120uL 120μL
EUR 360
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD252951A-200uL 200μL
EUR 630
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD252951A-20uL 20μL
EUR 109.5
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD252951A-60uL 60μL
EUR 214.5
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD82128A-120uL 120μL
EUR 360
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD82128A-200uL 200μL
EUR 630
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

RUSC1 Polyclonal Antibody

RD82128A-60uL 60μL
EUR 204
Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.

Polyclonal RUSC1 Antibody

APR13173G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RUSC1 . This antibody is tested and proven to work in the following applications:

RUSC1 Polyclonal Conjugated Antibody

C28956 100ul
EUR 476.4

RUSC1 Polyclonal Conjugated Antibody

MBS9440554-01mLAF350 0.1mL(AF350)
EUR 480

RUSC1 Polyclonal Conjugated Antibody

MBS9440554-01mLAF405 0.1mL(AF405)
EUR 480

RUSC1 Polyclonal Conjugated Antibody

MBS9440554-01mLAF488 0.1mL(AF488)
EUR 480

RUSC1 Polyclonal Conjugated Antibody

MBS9440554-01mLAF555 0.1mL(AF555)
EUR 480

RUSC1 Polyclonal Conjugated Antibody

MBS9440554-01mLBiotin 0.1mL(Biotin)
EUR 480

RUSC1 Polyclonal Antibody, HRP Conjugated

A60753
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

RUSC1 Polyclonal Antibody, FITC Conjugated

A60752
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

RUSC1 Polyclonal Antibody, Biotin Conjugated

A60751
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

Rabbit Polyclonal RUSC2 Antibody

TA319794 100 µg Ask for price

Rabbit Polyclonal RUSC2 Antibody

TA319795 100 µg Ask for price

RUSC2 (N-term) rabbit polyclonal antibody, Aff - Purified

AP53771PU-N 400 µl Ask for price

RUSC1 Rabbit pAb

E2515417 100ul
EUR 225
Description: Available in various conjugation types.

RUSC1 Rabbit pAb

A15417-100ul 100 ul
EUR 369.6

RUSC1 Rabbit pAb

A15417-200ul 200 ul
EUR 550.8

RUSC1 Rabbit pAb

A15417-20ul 20 ul
EUR 219.6

RUSC1 Rabbit pAb

A15417-50ul 50 ul
EUR 267.6

RUSC1 Rabbit pAb

MBS8549902-01mL 0.1mL
EUR 305

RUSC1 Rabbit pAb

MBS8549902-01mLAF405L 0.1mL(AF405L)
EUR 565

RUSC1 Rabbit pAb

MBS8549902-01mLAF405S 0.1mL(AF405S)
EUR 565

RUSC1 Rabbit pAb

MBS8549902-01mLAF610 0.1mL(AF610)
EUR 565

RUSC1 Rabbit pAb

MBS8549902-01mLAF635 0.1mL(AF635)
EUR 565

RUSC1 Rabbit pAb

A15417 20μL
EUR 1246.96

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

IRBAHURUSC1AAP38120UL each
EUR 240
Description: Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

IRBAHURUSC1AAP38200UL each
EUR 419
Description: Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

IRBAHURUSC1AAP51120UL each
EUR 240
Description: Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

IRBAHURUSC1AAP51200UL each
EUR 419
Description: Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4)(IHC, ELISA)

MBS8422027-INQUIRE INQUIRE Ask for price

Rabbit Anti Human RUSC1 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4)(IHC, ELISA)

MBS8422028-INQUIRE INQUIRE Ask for price

Rabbit Anti Human RUSC1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)

IRBAMLRUSC1AP09120UL each
EUR 320
Description: Rabbit Anti Human RUSC1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)

Rabbit Anti Human RUSC1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)

IRBAMLRUSC1AP09200UL each
EUR 530
Description: Rabbit Anti Human RUSC1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)

Rabbit Anti Human RUSC1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3)(Immunofluorescence)

MBS8424657-INQUIRE INQUIRE Ask for price

Rabbit Polyclonal Anti-RUSC1-AS1 Antibody

TA334977 100 µl Ask for price

RUSC1 Antibody

5411-002mg 0.02 mg
EUR 206.18
Description: RUSC1 Antibody: RUSC1, also known as NESCA, shares with the related protein RUSC2 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells. RUSC1 has also been shown to interact with IκB kinase- (IKK-) gamma, the regulatory subunit of the IKK complex that is required for NF-κB activation in many signaling pathways such as TNF-R or the TLR pathways. RUSC1 can also bind to the E3 ubiquitin ligase TRAF6, which then catalyzes RUSC1 polyubiquitination. Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma, RUSC1 may be a link in the IKK-gamma-mediated NF-κB activation pathway.

RUSC1 Antibody

5411-01mg 0.1 mg
EUR 523.7
Description: RUSC1 Antibody: RUSC1, also known as NESCA, shares with the related protein RUSC2 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells. RUSC1 has also been shown to interact with IκB kinase- (IKK-) gamma, the regulatory subunit of the IKK complex that is required for NF-κB activation in many signaling pathways such as TNF-R or the TLR pathways. RUSC1 can also bind to the E3 ubiquitin ligase TRAF6, which then catalyzes RUSC1 polyubiquitination. Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma, RUSC1 may be a link in the IKK-gamma-mediated NF-κB activation pathway.

RUSC1 Antibody

24975 100ul
EUR 479

RUSC1 Antibody

24975-100ul 100ul
EUR 468

RUSC1 Antibody

1-CSB-PA871585LA01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against RUSC1. Recognizes RUSC1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

RUSC1 Antibody

1-CSB-PA020596GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against RUSC1. Recognizes RUSC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

RUSC1 Antibody

DF16016 100ul
EUR 420

RUSC1 Antibody

DF16016-100ul 100ul
EUR 280

RUSC1 Antibody

DF16016-200ul 200ul
EUR 350

RUSC1 Antibody

E94571 100μg
EUR 255
Description: Available in various conjugation types.

RUSC1 Antibody

E308250 200ul
EUR 275
Description: Available in various conjugation types.

RUSC1 antibody

70R-20048 50 ul
EUR 289
Description: Rabbit polyclonal RUSC1 antibody

RUSC1 Antibody

MBS9403125-01mL 0.1mL
EUR 495

RUSC1 Antibody

MBS9403125-5x01mL 5x0.1mL
EUR 2075

RUSC1 Antibody

MBS8500972-01mg 0.1mg
EUR 325

RUSC1 Antibody

MBS8500972-01mLAF405L 0.1mL(AF405L)
EUR 565

RUSC1 Antibody

MBS8500972-01mLAF405S 0.1mL(AF405S)
EUR 565

RUSC1 Antibody

MBS8500972-01mLAF610 0.1mL(AF610)
EUR 565

RUSC1 Antibody

MBS8500972-01mLAF635 0.1mL(AF635)
EUR 565

RUSC1 Antibody

MBS151353-01mg 0.1mg
EUR 445

RUSC1 Antibody

MBS151353-5x01mg 5x0.1mg
EUR 1965

RUSC1 Antibody

MBS1495824-005mg 0.05mg
EUR 190

RUSC1 Antibody

MBS1495824-01mg 0.1mg
EUR 270

RUSC1 Antibody

MBS1495824-5x01mg 5x0.1mg
EUR 1205

RUSC1 Antibody

MBS9631304-01mL 0.1mL
EUR 260

RUSC1 Antibody

MBS9631304-02mL 0.2mL
EUR 305

RUSC1 Antibody

MBS9631304-5x02mL 5x0.2mL
EUR 1220

RUSC1 Antibody

MBS9633687-1mg 1mg
EUR 375

RUSC1 Antibody

MBS9633687-5x1mg 5x1mg
EUR 1545

RUSC2 Polyclonal Antibody

27844 100ul
EUR 439

RUSC2 Polyclonal Antibody

27844-100ul 100ul
EUR 302.4

RUSC2 Polyclonal Antibody

27844-50ul 50ul
EUR 224.4

RUSC2 Polyclonal Antibody

E912904 100ul
EUR 225
Description: Available in various conjugation types.

RUSC2 Polyclonal Antibody

MBS9133005-002mL 0.02mL
EUR 200

RUSC2 Polyclonal Antibody

MBS9133005-005mL 0.05mL
EUR 255

RUSC2 Polyclonal Antibody

MBS9133005-01mL 0.1mL
EUR 345

RUSC2 Polyclonal Antibody

MBS9133005-02mL 0.2mL
EUR 545

RUSC2 Polyclonal Antibody

MBS9133005-5x02mL 5x0.2mL
EUR 2265

Functional enrichment analysis showed that expression of high Zac1 associated with epithelial-mesenchymal transition (EMT), which was subsequently observed in clinical characteristics and metastatic carcinoma samples using immunohistochemical staining. Correspondingly, hypomethylation CpG islands in the promoter Zac1 observed in samples with high Zac1 expression in cervical carcinoma.