Xpc Antibody Rabbit

Lab Reagents

Human IgG antibody Laboratories manufactures the xpc antibody rabbit reagents distributed by Genprice. The Xpc Antibody Rabbit reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact rabbit Antibody. Other Xpc products are available in stock. Specificity: Xpc Category: Antibody Group: Rabbit

Rabbit information

XPC siRNA

20-abx940004
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

XPC siRNA

20-abx940005
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

XPC Antibody, HRP conjugated

1-CSB-PA026217LB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against XPC. Recognizes XPC from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

XPC Antibody, FITC conjugated

1-CSB-PA026217LC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against XPC. Recognizes XPC from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

XPC Antibody, Biotin conjugated

1-CSB-PA026217LD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against XPC. Recognizes XPC from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Anti-XPC (6D11)

YF-MA16082 100 ug
EUR 363
Description: Mouse monoclonal to XPC

XPC Polyclonal Antibody, Biotin Conjugated

A53793 100 µg
EUR 570.55
Description: The best epigenetics products

XPC Polyclonal Antibody, FITC Conjugated

A53794 100 µg
EUR 570.55
Description: kits suitable for this type of research

XPC Polyclonal Antibody, HRP Conjugated

A53795 100 µg
EUR 570.55
Description: fast delivery possible

Mouse Xpc ELISA KIT

ELI-17531m 96 Tests
EUR 865

Human XPC ELISA KIT

ELI-40545h 96 Tests
EUR 824

Mouse XPC shRNA Plasmid

20-abx973421
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human XPC shRNA Plasmid

20-abx955132
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Xpc ORF Vector (Mouse) (pORF)

ORF061960 1.0 ug DNA
EUR 506

Xpc ORF Vector (Rat) (pORF)

ORF079210 1.0 ug DNA
EUR 506

XPC ORF Vector (Human) (pORF)

ORF035983 1.0 ug DNA
EUR 95

XPC ELISA Kit (Human) (OKCD01514)

OKCD01514 96 Wells
EUR 792
Description: Description of target: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts. XPC:RAD23B contacts DNA both 5' and 3' of a cisplatin lesion with a preference for the 5' side. XPC:RAD23B induces a bend in DNA upon binding. XPC:RAD23B stimulates the activity of DNA glycosylases TDG and SMUG1. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.114 ng/mL